is there a database where I can find the sequences of the hypervariable domain of immunoglobulins and the sequences of the related antigens? Thank you


There are a number of databases that exist, though the one you would want to use will likely depend on what you need it for. The one that's recommended at my university is IgBlast, associated with The National Center for Biotechnology Information (NCBI), however I've seen IMGT as a recommended source, as well; it seems to have a wider array of tools. That being said, I can't say which you might find more beneficial, as I'm uncertain as to how you'd be using the resource.

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  • $\begingroup$ essentially I am interested in the primary sequence of the variable regions of the immunoglobulins (let's say GALMF) and the corresponding antigenic primary sequence (let's say CHYR), this sort of association. Thank you, I will have a look at those databases. $\endgroup$ – Gigiux Jul 16 '17 at 9:12
  • $\begingroup$ actually, these databases are blasting tools to search for patterns. I am looking for a list of sequences hits with both TCR of Ig and related antigens, if any. $\endgroup$ – Gigiux Jul 16 '17 at 9:17

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