I am trying to write out my research proposal about a project in C.elegans. There are multiple mutants of the factor that I want to study, each with different mutations. I know that a mutation that abolishes the promoter and transcription start site of the gene will most likely be a null mutant. But what about strains that have internal deletions? For example, if I were to generate mutants missing specific exons such that there was a predicted ORF for the gene product, is this transcript automatically targeted for nonsense mediated decay? I was told that this was a C.elegans specific process (deletion mutants are often protein null?), but I am having trouble finding this information.