1
$\begingroup$

I know that there is existing research on ultrasound-induced transient cavitation bubbles that mechanically denature DNA by generating violent shock waves locally in solution.

I would like to know if it is possible for non-cavitating ultrasound to denature short strands of DNA, ~20 base pairs in length (please cite sources, if possible). The mechanism should be mechanical, without involving thermal or cavitation effects of ultrasound. The ultrasound acts as a pressure wave, of the order of 10 MPa, and the DNA helices require a force of ~15 pN to initiate unzipping. I just need proof that this has been successfully demonstrated.

Thank you in advance.

$\endgroup$
  • $\begingroup$ Does DNA denature? $\endgroup$ – 4D Neuron Aug 14 '17 at 15:24

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Browse other questions tagged or ask your own question.