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I read somewhere that the Malate aspartate shuttle transfers the electrons to complex 1 in the ETC while Glycerol phosphate shuttle uses complex 2. Does anyone know if this is true? Also a lot of textbooks state that complex 2 can bypass complex 2. Does anyone know if this is true? I have seen this statement in the book Biochemistry by Voet and Voet.

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  • $\begingroup$ Hello! thank you for the answer. But do you know if it is possible for these two complexes to bypass each other? $\endgroup$ – sundari elango Sep 11 '17 at 12:42
  • $\begingroup$ I think that reducing equivalents 'feeding in' at Complex II effectively 'bypass' Complex I (electrons from the succinate dh reaction, for example) but AFAIK reducing equivalents passed to Complex I cannot bypass Complex II. ("Complex I is a complex one, but Complex II is complex too", as someone once put it). $\endgroup$ – user1136 Sep 11 '17 at 13:17
  • $\begingroup$ Thank you. Please let me know if you have any references for this above mentioned bypassing. $\endgroup$ – sundari elango Sep 13 '17 at 6:03

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