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I came across "bis-tris" buffer in Rodney Boyer's Biochemistry Laboratory book and tried looking it up. Then I found that there's bis-tris methane and bis-tris propane that are both buffers. What exactly are they used for and are the usages different?

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They have different acid dissociation equilibria and so buffer at different pH.

                    pKa1    pKa2
Bis-Tris methane    6.5     -
Bis-Tris propane    6.8     9

[source]

The two titratable secondary amines of Bis-Tris propane make it usable over a wider pH range.

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