Is it possible to surpass/decay cell death. For example to disable the process muscles cells death, by tweaking the transduction pathways:

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If it's not possible in our age Medicine, what it would take to do such thing in theory. The idea is to tweak the cell dying mechanisms for example to preserve neural and muscle cells for longer time. I am also curious how to disable a pathway or part of it.

  • $\begingroup$ Or maybe we could block cell death to increase cell death?! $\endgroup$ Commented Nov 29, 2017 at 0:35

1 Answer 1


Yes; It is possible to inhibit cell death.

There are several possibilities, of which many - as correctly recognized by you - involve changes in the activity of the cell death pathway (or related ones);

For a long (but still incomplete) list of commercially available drugs that inhibit cell death, please see: https://www.sigmaaldrich.com/life-science/cell-biology/cell-biology-products.html?TablePage=9559839

P.S.: Note that selectively inhibiting a pathway (note: not only cell-death) in only one cell type (or tissue - as you hinted at) usually requires a lot of tests and experimentation and isn't trivial.

  • $\begingroup$ How does the process of disabling a pathway work? $\endgroup$
    – 0x90
    Commented Nov 28, 2017 at 5:57
  • $\begingroup$ the processes will be highly drug and target specific $\endgroup$
    – tsttst
    Commented Nov 28, 2017 at 16:45

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