Neurotransmitter receptors are typically distributed on the dendrite and the soma of a neuron (and only occasionally on the axon):
- at excitatory synapses (more distal)
- at inhibibitory synapses (more proximal)
Does this rule of thumb also hold for neuromodulator receptors:
- excitatory → more distal
- inhibitory → more proximal
And are they clustered (like ligand-gated ion channels at synapses)?