I am trying to find information on Prostaglandin F2-alpha, specificaly production in men. Could somebody explain how this prostaglandin is produced? What types of cells are producing it, production signaling? Any books on this subject?


As I know:

One of the most important chemical mediators are prostaglandins that in vivo act on different cell receptors and have different effects on the body. Prostaglandins are twenty-carbon lipid molecules and structurally similar to cholesterol. Prostaglandins have different types, such as F2, E2 alpha, PGI2, and so on.

A phospholipase enzyme converts phospholipids of cell membranes into arachidonic acid. The arachidonic acid within the cyclooxygenase enzyme or Cox (both type 1 and 2) can be converted to prostaglandins.

PGF2alpha has functions in uterus contraction and bronchoconstriction, so I think both uterus and lung cells produce it.

I have no special information about production of PGF2alpha in men.

  • $\begingroup$ I think it is incorrect to say that prostaglandins are structurally similar to cholesterol. $\endgroup$ – Alan Boyd Feb 8 '13 at 16:39

PubChem is a good resource for finding out more about compounds of pharmaceutical interest:


  • $\begingroup$ This is more of a comment than an answer to the question. To make it an answer you should pick out some key points from the article and include them in your post. $\endgroup$ – Rory M Feb 9 '13 at 11:35

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.