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I was always curious how it was determined that bacterial plasmids were circular, since there isn't an obvious way to find this out. I heard somewhere that there was a difference when gel electrophoresis was conducted. Could anyone give an explanation?

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  • $\begingroup$ Where did you hear this? Having a reference would help. $\endgroup$ – kmm Dec 25 '17 at 14:53
  • $\begingroup$ i searched google that exact question and the first few pages talked about gel electrophoresis but sadly none of them gave a clear explanation $\endgroup$ – toebee Dec 26 '17 at 14:42

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