Just wondering if Vitamin B12 is necessary for the body to utitlize folate. My husband is on Methotrexate for rheumatoid arthritis, a medicine which is known to destroy folate. The doctors therefore prescribe high dose folic acid. He also, however, has a geographic tongue which is supposedly due to B12 defiency. If he is deficient in B12, and yet if B12 is necessary for folate absorption, the extra folic acid is presumably doing no good. Whether the two vitamins are essential co-factors is interesting to know because I've just read that folic acid deficiency gives people a 69% higher risk of heart disease. And he's just had a massive heart attack.
I can't seem to find the answer on standard search engines, would be grateful to know whether B12 is needed to utilize folate. Many thanks.