if experimentally one induces smooth muscle contraction on an artery and cause it to constrict, keeping the cardiac output same and also the arteriolar resistance(total peripheral resistance) the same will the pressure in the artery increase or decrease?

  • $\begingroup$ What do you think? $\endgroup$ – JM97 Jan 9 '18 at 15:03
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    $\begingroup$ i think in an isolated scenario such as above wherein all other factors are same blood pressure will increase in that artery because vasoconstriction will cause an increase in active tension in the walls of artery(contraction of smooth muscle) and radius will be decreased so using laplace law(pressure=tension/radius) pressure will increase am i right? $\endgroup$ – user141356 Jan 9 '18 at 17:10
  • $\begingroup$ another way to look at this is artery expands when blood is pumped in(pressure energy is converted to elastic potential energy) but vasoconstriction will increase the active tension and will cause stiffening of the artery hence it won't expand and pressure energy will not be converted to elastic energy and hence pressure will be high $\endgroup$ – user141356 Jan 9 '18 at 17:14
  • $\begingroup$ Is Laplace law applicable in this case?( Fluid moving). What are your thoughts on applying Bernoulli's principle? $\endgroup$ – JM97 Jan 10 '18 at 2:42
  • $\begingroup$ bernoullis cannot be applied because vessels are not rigid tubes and scenario is not ideal ie resistance is present and laplace law can be used i guess because it just relates pressure radius and tension in the vessel irrespective of flow or not $\endgroup$ – user141356 Jan 10 '18 at 6:03

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