How does serotonergic (5-HT2A specific) psychedelia work? I've read that there are some theories that it might involve the induction of a glutamate release in certain regions of the brain involved in perception.


1 Answer 1


Brenton, the linked pdf is called "Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens". It goes into detail on a a few basic behavioral responses. I don't know what your background is so if you need help understanding parts point them out to me and I'll give it a go.


https://docs.google.com/file/d/0B0JUrCVOms3MdzdlYmh0SnBmOHc/edit (I'm hosting the pdf on my Google Drive if you aren't able to see the link hosted by the NIH).

  • $\begingroup$ Thanks, mate, if I find the article in question sufficiently helpful I'll accept your answer and up-vote it. I'm grateful that you quoted a reliable source. Of course you can't just take people's word on these Q&A sites without some proof because you can't be certain of their qualifications regardless of what they claim. I probably won't need too much help in understanding it, I usually understand such articles, but if I need help I'll ask. $\endgroup$
    – Josh Pinto
    Commented Jan 30, 2013 at 23:10

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