We learned in our lecutre, that aquaporin lets Water pass, but blocks Ions like H+ and unpolar molecules like CO2 and H2. The reasons for the Ion blocking are comprehensible, but I dont get, why less-than-water-polar molecules are blocked. Our professor said, it has something to do with the water molecules are orient in the aquaporin towards the positively charged n-terminus of the alpha helix, but why is that an advantage compared to non polar not charged molecules?

  • $\begingroup$ Electrostatics. $\endgroup$ – user37894 Mar 29 '18 at 15:19

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