When we conduct mosquito infection studies we typically mix blood and virus rather than using viraemic blood from naturally infected hosts. I'm looking for a paper I read some years ago which demonstrated that virus mixed with blood containing antibodies to that virus (not to mosquito midgut or salivary gland antigens) resulted in a lower proportion of infectious vectors than virus mixed with blood that does not contain those antigens. Unfortunately I don't seem to have kept a copy and now every search I conduct only throws up results to the aforementioned studies of anti-midgut or anti-SG antibodies. The nearest thing I can find is this, which looks at inhibition during intrathoracic inoculation (a completely different route of infection which is not particularly realistic, although we sometimes use it to boost the infection rate).



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