I read this article in the following:
... Mice that have been reconstituted with geneX-transduced cells
Now, someone who is not familiar with animal sciences, what does this exactly mean? It is in the context of hematopoietic stem cells. I have two possible interpretations as a result:
- An Hematapoetic stem cell with geneX was successfully transplanted into the mouse
- The mouse cells (from the embryo) were engineered to contain geneX, and hence the mouse has been reconstituted with geneX transduced cells
Are any of these correct? If I am wrong please let me know!