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The gnomAD browser provides information on variants of genes (in this link, for the SAMD11 gene.) The report on a particular variant, like this one, includes the information in the header that says (for example): "This variant falls on 5 transcripts in 2 genes."

What does this mean? In particular, how can a variant occur on more than one gene? Isn't such a variant a variant of a particular gene -- SAMD11 in this case?

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In this particular case, there is another unannotated gene at the same locus, running in the opposite direction as SAMD11.

http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000268179;r=1:865499-865579;t=ENST00000598827

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