My colleagues have measured Kcat for 29 mutants of a certain enzyme and they've studied the possible impact of those mutations on the protein's physicochemical properties through computational models.

Is anyone familiar with research that looks at ways to link both pieces of information?

Found this review. Would appreciate if anyone has something more recent but it looks like a good starting point

  • $\begingroup$ You have to provide more details on what kind of connection you are looking for. Your question is a bit unclear to me. $\endgroup$ – WYSIWYG May 4 '18 at 13:07

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