I am using plant extract of Ajuga parviflora and found out that it possess anti-diabetic properties by using alpha-amylase inhibitory assay. I used various concentration 250 µg/ml(29% inhibiton of alpha-amylase), 500µg/ml(37%),750µg/ml(46%) and 1000µg/ml(63%). Basically, alpha-amylase results in increase in glucose level after eating food. So i wanted to know that how could i find out that what is the best concentration of my plant extract to be used as drug.
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$\begingroup$ This sounds like a homework question. Is it? $\endgroup$– DavidJun 9, 2018 at 8:05
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$\begingroup$ No, i am in my final year of my btech working on a plant and when a plant report some property then it is better if we can also give its best concentration. $\endgroup$– roxaiteJun 9, 2018 at 8:11
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1 Answer
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You have to try to determine the best concentration.
Usually there are multiple clinical trials, first in animals, then in humans to
- figure out the effective dose
- look for side effects
- compare the new drug's efficacy with existing drugs
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$\begingroup$ I think this is better as a comment as it doesn't answer the question which in any case looks very like a homework question. $\endgroup$– DavidJun 9, 2018 at 8:08
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$\begingroup$ @David Actually I started writing a comment first and was expecting a "please don't answer in comments" response :) And it didn't occur to me this could be homework. $\endgroup$– ArsakJun 9, 2018 at 8:11
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$\begingroup$ @David Owh, and the answer was: You have to try. $\endgroup$– ArsakJun 9, 2018 at 8:14
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$\begingroup$ @SolarMike Yeah, was confused by the man/men and woman/women plural. $\endgroup$– ArsakAug 9, 2019 at 8:22