There is a problem I stumbled upon when doing a lesson on molecular genetics (Grade 12 level).
I don't understand how it got to the mRNA codon considering how RNA polymerase creates mRNA. From what I know already RNA polymerase reads the anti-sense/template strand (
3`-5`strand) and synthesizes mRNA in a
For example, using the first column with the DNA codon
5`-TAC-3`, I would automatically convert it to
3`-5` complementary anti-sense strand because of the nature of the enzyme. It would be
3`-ATG-5`. Now using that anti-sense strand I would find the complementary base pairs and the mRNA strand would be
5'-UAC-3'. This is not consistent with the example given by the lesson. I can understand how to get to the answer (just find the complimentary base pairs of the DNA codon given) but it goes against what I know.
Now if the table said (
3`-5`) instead of (
5`-3`) it would make sense. Am I misunderstanding a fundamental concept?