I am trying to find a 3D rendering or list of molecules by volume in a cell (originally I was searching for human, but I'll take any at this point!). I understand the open-endedness of the question: what type of cell? During which phase? Under what conditions? etc.

What I am looking for, if such a thing exists, is as accurate-as-can-be list of structures/particles/macromolecules/ions/etc by volume in the protoplasm.

"Inside a living cell" by DS Goodsell is a step in the right direction but nearly 20 years old at this point.

"Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm" is another step in the right direction.

Anything related to this query would be appreciated!

Thanks for your help!

  • $\begingroup$ For some components, you can find it here: bionumbers.hms.harvard.edu $\endgroup$ – tsttst Aug 18 '18 at 20:47
  • $\begingroup$ Your title and question seem to be different. Your title would be off-topic as it is not about biology per se, but as it seems to be a concern I shall comment on it. The reason, I would think, is that modern biology — especially cellular and molecular biology — is not about classification. It is about understanding how things work. So why would any modern biologist do such a thing? Presumably you have a reason for wanting such a list, but I can't imagine why you would want the comparative volumes of all proteins, for example, even if this were known. Perhaps you could explain. $\endgroup$ – David Aug 19 '18 at 14:38

The various data related to dimensions and volumes of structures\organelles\macromolecules and cells themselves could be obtained from BioNumbers. For example, please see in the table below the information on volumes of COS-7 (monkey kidney tissue):

The details can be got at Applying systems-level spectral imaging and analysis to reveal the organelle interactome, by Valm A.M. et al


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