How could you use nuclear and mitochondrial DNA samples run through electrophoresis to determine parental lineage.


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Before DNA sequencing was widely available, some lineage information could be determined using restriction fragment length polymorphism, a kind of "DNA fingerprinting". https://en.wikipedia.org/wiki/Restriction_fragment_length_polymorphism

Analyzing nuclear DNA would give information about both parents, while mitochondrial DNA would give information specifically about maternal lineage, as we inherit our mitochondrial DNA only from our mothers.


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