1
$\begingroup$

In the GWAS analysis, my animal sample phenotype is whether an individual dies or survives. And I have every sample death time. How do I set the phenotype in GWAS analysis?

$\endgroup$
1
$\begingroup$

Simply, First of all, you can group samples as survived animals and dead samples and you have a binary phenotype.

In a different approach, you can use survival time (time to death) as an ordinal variable phenotype. If you want you can utilize survived sample by assign a large death time value to them.

In the third approach, you can cluster the survival time (time to death) into the desired $n$ groups by the simple procedure like $k$-means. and you have coarse grain ordinal variable you can add survived sample group at the end of The Spectrum.

$\endgroup$

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.