0
$\begingroup$

enter image description here

If the following loci indicated the presence of an SNP in flu strains, is Locus 2 and Locus 3, which are located 10 bp apart in linkage disequilibrium?

"When alleles and molecular markers are associated with each other at a frequency that is significantly higher than expected by random chance, they are said to exhibit linkage disequilibrium" Brooker's Genetics

Both loci seem to be linked, but how do I determine if it is significant enough to be considered in disequilibrium or not.

$\endgroup$
2
$\begingroup$

As per the definition you gave, you check whether there is a statistical association between the two. If knowing when allele is present at a locus does not affect the probability of finding a given allele at the other locus, then they are independent (there is no association). Otherwise, there is an association and hence the two loci are in linkage disequilirium.

See wikipedia > Linakge disequilibrium for more info.

$\endgroup$

Your Answer

By clicking "Post Your Answer", you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.