Would some inhibitors of viral enzymes work against common cold viruses? Are there any studies? What could a treatment look like?
A human enzyme involved in the production of rhinovirus capsids has been successfully inhibited.
Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus https://www.nature.com/articles/s41557-018-0039-2
The article also says that targeting a human enzyme could be more efficient since the risk of mutation is lower compared to a virus enzyme.