0
$\begingroup$

I could not find any comprehensive review about this; I'm interested in comparing the duration of viral cycles from the entry in the host cell to the release of a mature virion. In particular, I am interested in finding an example of a really, really fast viral cycle (in eukaryote cells), either in a natural host or in a laboratory setting.

Some viruses are "slow"; for example, lentiviruses require a reverse transcription, followed by an integration step, transcription, specific targeting mechanisms... it takes about 24h for HIV, for instance (Mohammadi et al, PLoS Pathogens, 2013).

For certain viruses, in the right conditions, this time can go down to a few hours; for example, the Influenza cellular cycle takes about 8-10 hours when the virus is propagated in MDCK cells (Gaush & Smith, Appl. Microbiology, 1968).

What is the key determinant (if not purely replicative constraints) of viral cycle duration? What are the fastest viral cycles out there?

$\endgroup$

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Browse other questions tagged or ask your own question.