Is there any known example in a cell where a protein is activated by the hydrolysis of GTP to GDP, rather than the reverse in which a protein is activated when GTP binds to an inactive GDP-bound protein?

  • $\begingroup$ I can't answer this question with certainty, but I expect the answer is "no" as once nature has found a way of regulating processes, it is easy to clone that than mix things up by turning them on their head. But biology is not physics, and is full of exceptions. There may be one here, but I would be very surprised. $\endgroup$ – David Mar 31 at 22:19

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