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I want to know how can a particular base sequence like the TATA box in the -10 region of a gene is able to regulate a protein's function like RNA polymerase? What kind of interaction really occurs?Is it always that some other proteins bind to these sequences and that affects dynamics of RNA polymerase or does the strand directly interacts with RNA polymerase?

In lecture prof said that transcription factors bind this regions and thats all I know about what is the function of these regions.

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    $\begingroup$ Welcome to SE Biology. Please read the Help on Asking questions, and particularly our policy on Homework questions, which this looks suspiciously like. In any case you need to show evidence that you have tried to find the answer yourself. The Wikipedia entry on TATA box is a reasonable place to start, or Berg et al. Biochemistry. If you still have problems after reading these, let us know what they are. $\endgroup$ – David Apr 15 at 11:17

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