Would an intravenous injection of insulin + glucose result in significantly quicker replenishment of exhausted glycogen stores than an injection of glucose alone?
This is a strictly theoretical question and I'm aware of serious dangers of intravenous insulin (Diabetes Spectrum). It is to help with writing a story in which a quick recovery from exhaustion is needed.
After heavy exercise, during which the glycogen stores are depleted, the glycogen can be replenished fully in about a day by consuming high-carbohydrate meals (PubMed).
According to one study, intravenous glucose stimulates glycogen synthesis, but there is no timing mentioned.
Would adding insulin into glucose injection further accelerate glycogen synthesis and for how much? Is there any minimal time needed for glycogen synthesis regardless of the amount of glucose and insulin available?
The added insulin would probably inhibit the natural secretion of insulin from the pancreas, so does intravenous insulin injection even make sense?