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The Trans-activator of transcription (Tat) plays a crucial role in regulating the transcription process of HIV-1. But which state of the Long Terminal Repeat (LTR) produces Tat? Is it the "intermediate state" (or basal transcription state) or the "active state" (or the activated transcription state)? or perhaps both produce "Tat"?

Any reference would be much appreciated.

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    $\begingroup$ Your question is a bit unclear. What do you mean by state of LTR? LTR is a structural motif. Can you please add some context to clarify the question? $\endgroup$ – WYSIWYG May 15 at 11:59

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