Dopamine is also known as a prolactin-inhibiting hormone, which keeps prolactin levels in the body in check. However, during orgasm, dopamine is released to make the experience pleasurable. I know that prolactin is released as well. Don't they counteract each other? The prolactin also has a meditative effect, which from what I know causes a refractory period where another orgasm can't be achieved. Does prolactin inhibit dopamine release too?