This image is in the textbook, Molecular Biology of the Cell. I understand why the start and stop transfer sequences must alternate, but why is there 2 consecutive start transfer sequences at the N terminal of the protein? How does it get embedded in the membrane via translocation?

The text describes how single-pass and double-pass transmembrane proteins work clearly but using the same mechanism (via Sec61 translocon), I can't figure out how this multipass transmembrane protein gets translocated.

Thank you.


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