GENESIS simulation software http://genesis-sim.org/ is designed for neurobiological systems and it is able to inculude in the simulation the different resolution levels - starting from the molecular interaction and ending with neuronal interaction. My question is - can GENESIS be applied to other tissues, are there efforts to do this and what kind of adaptations should be made? I guess that GENESIS is already capable to include full diversity of the molecular interaction patterns that are common to all cells. But some tuning is necessary for models at the cellular and multi-cell level? I guess that there is lack of dedicated GENESIS-level software for other tissues and systems.