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I have read in in the original paper that in the year 1983 a research group in Kiel, Germany (that's where the Ki- in the name comes from) developed monoclonal mouse antibodies against Hodgkin lymphoma cells in multiple 24-well plates. If I understand correctly they were able to isolate antibodies from 63 wells and divided them into 493 microtiters into several 96-well microtitre plates. Of these 493 titres, 164 cell batches were chosen for further investigation and expanded. Somehow Ki-67 emerged from there, but why this number? Who gave it that name and why?

A teacher once told us in med school, the cells producing the antibodies were found in well 67, but I cannot find any source to back up that claim.

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  • $\begingroup$ There's this article, but who knows where these authors got the idea from... $\endgroup$ – canadianer Oct 9 at 21:58
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From Wikipedia: "The name is derived from the city of origin (Kiel, Germany) and the number of the original clone in the 96-well plate".

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    $\begingroup$ That statement in the wikipedia article is unsourced ... $\endgroup$ – tyersome Oct 12 at 19:15

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