2
$\begingroup$

I have read in in the original paper that in the year 1983 a research group in Kiel, Germany (that's where the Ki- in the name comes from) developed monoclonal mouse antibodies against Hodgkin lymphoma cells in multiple 24-well plates. If I understand correctly they were able to isolate antibodies from 63 wells and divided them into 493 microtiters into several 96-well microtitre plates. Of these 493 titres, 164 cell batches were chosen for further investigation and expanded. Somehow Ki-67 emerged from there, but why this number? Who gave it that name and why?

A teacher once told us in med school, the cells producing the antibodies were found in well 67, but I cannot find any source to back up that claim.

$\endgroup$
1
  • $\begingroup$ There's this article, but who knows where these authors got the idea from... $\endgroup$
    – canadianer
    Commented Oct 9, 2019 at 21:58

1 Answer 1

5
$\begingroup$

From Wikipedia: "The name is derived from the city of origin (Kiel, Germany) and the number of the original clone in the 96-well plate".

$\endgroup$
2
  • 2
    $\begingroup$ That statement in the wikipedia article is unsourced ... $\endgroup$
    – tyersome
    Commented Oct 12, 2019 at 19:15
  • $\begingroup$ Yes that's the legend, but I want details... $\endgroup$ Commented Nov 2, 2019 at 20:44

You must log in to answer this question.

Not the answer you're looking for? Browse other questions tagged .