I was reading about mRNA export process. I came to know that only 36% of synthesized mRNA transport events at Nuclear Pore Complexes(NPC) of the nuclear membrane get successful in crossing to the cytoplasm. I have heard that transcription machinery is a highly accurate one and so why would NPCs want to regulate mRNA transport like this?
Is NPC acting as a quality checker? Are there any errors mRNAs facing in between the transcription and meeting NPCs? (Please share related literature, if you find some.)
Any other hypothesis someone would want to share?