In CNN's video Scientist says Coronavirus vaccine could be ready by 2021 after about
00:25 'Robin Shattock, the Head of Mucosal Infection and Immunity at Imperial College London' says:
We were able to access the sequence that was published by Chinese scientists and made globally available, which was a tremendous thing to do. And we went from that sequence to identifying part of the sequence that encodes for the surface proteins of the virus. And we’re using that sequence to manufacture our vaccine.
We’re using a particular approach where we make a synthetic vaccine based on RNA, so essentially it’s essentially genetic code, we package that in essentially a lipid droplet, and use that to inject in a muscle; it expresses that protein, and the body recognizes that as foreign and it makes protective antibodies.
I'm assuming that this is mRNA and so once it reaches the cytoplasm of the vaccine recipients muscle cells it will be expressed and somehow returned to the cells' membrane where it will be recognized as foreign by passing lymphocytes.
- Is this basically correct as far as it goes?
- If so, what causes the lipid droplet to fuse with muscle (or other) cells in the first place?