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I’ve been struggling the last couple of days to find reliable data on the average nucleus size of a human skeletal muscle cell. If I deduce it from pictures it should be in the range of 20 micrometers long and 3 micrometers in diameter but I need reliable data and a proper source.

Could anyone help me with this?

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  • $\begingroup$ Welcome to Biology.SE! You may find it beneficial to take the tour and then go through the help pages starting with How to Ask questions effectively on this site. Thanks! 😊 $\endgroup$ – tyersome Feb 21 '20 at 21:21
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The average "length" for normal human myonuclei is 11.75 µm according to the abstract for:

Watkins, S. C., & Culien, M. J. (1988). A quantitative study of myonuclear and satellite cell nuclear size in Duchenne's muscular dystrophy, polymyositis and normal human skeletal muscle. The Anatomical Record, 222(1), 6-11.

If you can get access to this paper it should have more information for you.

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  • $\begingroup$ If I am correct, the myoblast are combined into myocytes. Do you think I can assume that the nuclei stay the same size? $\endgroup$ – Pjotr Feb 22 '20 at 15:49
  • $\begingroup$ Sorry — I messed up. The results were for myonuclei in myocytes (I have no idea what I was thinking when I wrote myoblasts). Now corrected. $\endgroup$ – tyersome Feb 22 '20 at 18:10

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