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I am currently an A-level biology student — what I understand is:

B cells can either be independent of T cells or dependent on T cells for activation. The ones which are dependent on T cells require an activated T-helper effector cell to bind to the MHC II site of the B-APC.

However, a textbook stated that B cells are activated by interleukins produced by T cells.

Is this a simplification or are both process required for the activation of B cells?

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  • $\begingroup$ Welcome to SE Biology! Usually on this site we prefer if you can show in your question that you have performed a little bit of research on your own. This can consist of googling it or reading a couple of wikipedia pages. All this is to say: the answer to your question is in the "activation" section of the wikipedia page on B cells (en.wikipedia.org/wiki/B_cell#Activation). $\endgroup$ – Maximilian Press Mar 24 at 2:13

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