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On the left, is my histology book, on the right there's qoura (the internet). My histology textbook says that "unlike glycoproteins, proteoglycans have attached GAGs which often comprise a greater mass than the polypeptide core"

What I found on qoura is "The carbohydrate content of proteoglycans (10-15%) is far less than glycoproteins is (50-60%)"

I tried googling the question but couldn't find the answer so which of these is correct ?

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More context would be helpful, but it's possible the data from the Quora post was incorrectly transcribed from a table on this biotech site, which states that the carbohydrate content of proteoglycans is 50-60%, compared to 10-15% for glycoproteins.

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However, the first comment on that page suggests that the table was initially incorrect:

Hi Anne,

This is a great post, but the numbers for the carbohydrate content are reversed. It’s 50-60% for the proteoglycans and 10-15% for most common glycoproteins (and things like uromodulin and most mucins would be 30+% sugars).

Best,

Jared Gerlach

So that may be the source of confusion, here. It seems the commenter is an expert in the field of glycan research, so the table is likely correct.

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    $\begingroup$ Was the table edited afterwards ? Because the table shows 50-60% carbs in proteoglycans and 10-15% in glycoproteins which the writer and the commenter agree on $\endgroup$ – Jaja bae Apr 10 at 21:38
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    $\begingroup$ Yes, it seems that is the case. I've edited my answer to reflect that, thanks. $\endgroup$ – Dirigible Apr 10 at 21:42

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