FIIND - Domain with Function to Find.
What is the meaning of this name? Does it mean "Domain with an unknown function"?
I'm translating an article in which this domain is mentioned, and I found three different translations of the term into Russian: "Domain with an unknown function", "Domain with a search function", "Domain with identification function".
I think the first translation is the most logical one, but I'm asking just in case, because I'm not an expert in this field.
The NALP subfamily. Finally, a large subfamily of the CATERPILLAR proteins is composed of 14 NALPs (also called PANs36 or PYPAFs37; FIG 2.) and is characterized by the presence of an amino-terminal PYD. This modular architecture is found in NALPs 2–14 (short NALPs), whereas NALP1 contains an additional domain — which our group has designated FIIND (function to find) — and a CARD, forming a carboxy-terminal extension. With two notable exceptions (NALP1 and NALP3), the NALP genes are located in two clusters on human chromosomes 11p15 (NALPs 6, 10 and 14) and 19q13.4 (NALPs 2, 4, 5, 7, 8, 9, 11, 12 and 13) (TABLE 1). Interestingly, the 11p15.5 region is an important IMPRINTED region and has been implicated in the imprinting disorder Beckwith-Wiedemann syndrome and in various human cancers, including Wilm's tumour38.