I was studying a lecture on the effects of cytokines on hematopoiesis, and it uses these two terms often in the context of the effects of regulators on hematopoietic stem cells:

  • All repopulating bone marrow HSCs express a fibroblast growth factor (FGF) receptor that supports HSC expansion
  • TPO may has a role in promoting the survival of repopulating HSCs, however, it contributes to both generation and expansion of HSCs during definitive hematopoiesis.
  • Etc.

I looked online and honestly struggled to find any form of a definition on these two terms. They are used awfully alot though which makes it kinda weird too frankly.


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