I was reading some articles about CRISPR and the world of gene editing, but then a lot of questions for which I couldn't find any answer online came into my mind. Those are all about how far can we edit an organism. So here is the general question, followed by some other to narrow down a little bit this broad subject:
What are the limits of gene edition?
- Can one edit the genes in its entire body? (as a human, or a multicellular organism)
- What are the risks? I heard that some people who did try gene therapy ended up having some of their modified cells turned into cancer. Was is because of gene incompatibility or because of error during the gene editing process?
- Can we go as far as adding some chromosomes or changing an entire chromosome? For example, if a male human would like to change their sex, could they switch all their Y to an X?
EDIT: I decided to accept the answer from @MattDMo. However, I'm still interested in some development (clues with other technologies...)