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Commonly artificial organs are generated though stem cell technology. E.g. IPSC-technology. Cardiomyocytes (Heart cells) spontaneously beat and have been used to create organoids. To further define beating - 'spontaneously electrical contracting' but not 'pumping'.

Cell physiology methods are applied for the investigation of cardiac features. E.g. Contractile force, calcium cycling or electric signals are commonly done.

However, none have contained chambers. All cardiomyocyte organoids are 'balls of cells'.

Has a beating cardiomyocyte organoid with 'chamber/s' been generated? if not, why?

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    $\begingroup$ How do you define "beating"? I've been out of that research area for a bit so I'd have to research on my own, but my suspicion is that "beating" as in spontaneously electrically active and contracting "yes", beating as in pumping "no". $\endgroup$ – Bryan Krause Aug 5 at 17:12
  • $\begingroup$ Great question, you're absolutely correct. $\endgroup$ – Andrew Aug 5 at 21:39
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    $\begingroup$ I was asking you to please clarify your question - can you edit to do so? $\endgroup$ – Bryan Krause Aug 6 at 16:13

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