I'm looking for an enzyme that does not function as part of a complex in its active state. Preferably it also is not part of a kinase or other kind of activating cascade as well though I would appreciate any and all names that are not part of a complex in its active state. Also would be better if it does not require post translational modifications. Of course, pre translational modifications/ interactions at rna or dna level are all good. In eukaryotic genome but bonus points for human genome! Thanks!!

  • $\begingroup$ Ribozymes may answer your conundrum here. $\endgroup$ – Andrew Sep 9 '20 at 23:57
  • $\begingroup$ Ribozymes are made of 2 subunits though. I'm basically wondering if there is a protein with no quaternary structure and maybe even those little things I mentioned above. $\endgroup$ – Sarthak Garg Sep 10 '20 at 0:00
  • 2
    $\begingroup$ This seems like a XY problem $\endgroup$ – Bryan Krause Sep 10 '20 at 1:35
  • $\begingroup$ I'm not really sure how else to phrase unfortunately. But that's a good thing to learn about! Feel free to edit or advise and I'll comply! $\endgroup$ – Sarthak Garg Sep 10 '20 at 3:00
  • 2
    $\begingroup$ I can't really suggest an edit because I have no idea what problem you are trying to solve, and that's kind of the problem with XY questions. What is your goal? $\endgroup$ – Bryan Krause Sep 10 '20 at 3:29


Chosen because the esterase seems like a low energy reaction so it wouldn't need energetic co-factors.


Not sure if I should do a new answer or not.

  • $\begingroup$ Yeah. The Zn is a cofactor so technically doesn't add to the quaternary structure. I'll keep the question open in case someone identifies a completely isolated enzyme. $\endgroup$ – Sarthak Garg Sep 10 '20 at 3:02
  • $\begingroup$ @SarthakGarg , i have changed my answer. $\endgroup$ – Polypipe Wrangler Sep 10 '20 at 4:37

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.