As far as I know, neurotransmitters are proteins, so they should be secreted from the cell body of the neurons.

However, when I checked online, they say neurotransmitters are secreted in the axon terminal (pre-synaptic terminal). This is due to the incoming nerve impulse to the axon terminal, hence 'exciting' something to secrete the neurotransmitters with the help of ATP (abundant in mitochondria).

May I know what is the true location in which neurotransmitters are secreted?

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    $\begingroup$ It's usually helpful to include a link to where you found a particular piece of information, so other users can decide whether it is valid or not. This is better than 'checked online, they say....'. $\endgroup$ – user438383 Sep 10 '20 at 16:05

There are proteins (in truth, small peptides) released by neurons, but these are not the most typical or canonical type so I don't know where you got that information. Wikipedia has a list. Most are amino acids or derived from amino acids. They are transported into vesicles and then released when these vesicles fuse with the plasma membrane.

Neurotransmitters have to be released in the axon terminal. That doesn't mean that neurons can't also release growth factors and such in the vicinity of their cell body, but the entire function of a neuron is to transmit a message from one place to another (after some processing that occurs based on received input). Neurotransmitters are the way that message is released for most neurons, and axons are the typical "output" structures of a neuron.


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