Apologies if this is too basic of a question, but I am an electrical engineer, just getting into neuromodulation/neurostimulation.
For my senior project, I am trying to make a device that stimulates the sphenopalatine ganglion. I have read as much as I can online, but some basic questions seem to not be answered. Answers to any of these would be really really helpful, as well as any resources to continue my research:
- When I'm trying to 'stimulate' a neuron, I am really trying to trigger an action potential, correct?
- Can I just send current across the exterior of the membrane to trigger an action potential?
- Is is possible to stimulate a neuron without piercing the membrane? I know an action potential is the voltage across the membrane, so how can I change that voltage without piercing the membrane?
- I believe I need to record the action potentials of the neuron, to make sure that my device is targeting the correct location and working properly, is this possible without piercing the neuron?
- From the literature, I found that a 10 Hz electrical pulse works best for the sphenopalatine ganglion stimulation, but I am not sure how frequency plays a role in this.
Sorry again if that is a lot, but I am new to the field and have a lot of questions. Thanks in advance for any help!