I am an O blood group person meaning, I can donate my blood to all as I don't have any Antigen A and B. But my body does contain antibodies A and B right?

If they were along with the donor blood, wouldn't they cause clotting with the recipients blood?

We spent a whole period over this. My teacher said they probably remove the antibody before transfusion, but I couldn't find much info on that. I postulated that these antibodies can not work outside the donor body for some reason.

Thanks for the help


1 Answer 1


I quote from the below.

Groups and Red Cell Antigens


Laura Dean (page 7). Available at:


"Red blood cell incompatibility may also occur when the patient's RBC antigens are attacked by antibodies from the donor's plasma. This tends to be a minor problem because of the small amount of antibody present in the donated plasma, which is further diluted on transfusion into the recipient's circulation."

I dont think the antibodies are removed, but in countries with a good medical system I believe the matching blood type is always used.


  • $\begingroup$ "I dont think the antibodies are removed" But isn't O group still considered universal donor. Thanks for telling me it's only a minor problem $\endgroup$ Jan 18, 2021 at 17:19
  • $\begingroup$ O is universal donor. $\endgroup$ Jan 18, 2021 at 23:52

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