(Not sure if this should be on the medicine SE)
There've been plenty of medicines that no longer work because the target pathogen has evolved resistance, e.g. penicillin is no longer an effective antibiotic. Have there been any treatments that no longer work because the human body evolved?
I imagine since evolution is a slow process, if there is such a medicine, it would've been around since antiquity (to give evolution the most time possible to work).