Skip to main content

Questions tagged [animal-models]

Animals used, for both practical and ethical reasons, to study biological systems and draw conclusions about homologous processes in other organisms, especially humans.

Filter by
Sorted by
Tagged with
0 votes
1 answer
49 views

How to understanding the mouse strains name and differences in mouse strains used in biology

I am currently working with various mouse strains in my biological research and I am encountering some confusion regarding their nomenclature and differences. I understand that the different names ...
0 votes
0 answers
31 views

Looking for a recommendation: Anatomical diagrams of animals commonly used in laboratory testing (potential surgical procedure emphasized)

I'm interested in either a book or a place to find well-drawn diagrams of animal anatomy. The emphasis if possible would be on anything which includes material related to the nervous system of ...
0 votes
0 answers
25 views

Are organisms that are genetically modified with a deletion classified as "transgenic"?

Imagine you delete a genomic region in a zygote with a CRISPR plasmid to generate an F1 animal with a genomic deletion. The animal should be considered transgenic because of the presence of the ...
3 votes
0 answers
68 views

Database of unique attributes of biological model systems

I am interested in deviations from standard eukaryotic biological mechanisms: Sperm chromatin lacks nucleosomes, and are instead highly condensed by protamines. (most eukaryotic chromatin has ...
4 votes
1 answer
119 views

Animal models to study depression [closed]

Is there a non-invasive animal model to study the pathogenesis (i.e., the development of) depression?
4 votes
1 answer
175 views

Is it possible to establish a newer animal model completely based on Bioinformatics studies?

I wanted to know, if it is possible to prove a new organism as an animal model for any human disease by only Bioinformatics methods like NGS and Structural bioinformatics. For Example, let's say ...
8 votes
1 answer
2k views

“The rhesus macaque is pretty much the closest thing we have to humans” — why?

Vincent Munster (researcher at Oxford) states (in the context of testing vaccines for COVID-19): The rhesus macaque is pretty much the closest thing we have to humans I thought chimpanzees and ...
5 votes
2 answers
432 views

Are Zebras white with black stripes, or black with white stripes?

I'm not sure it makes sense, but are zebras black or white below the surface?
1 vote
0 answers
37 views

Is there any reliable data about the correlation between the size of a species and number of individuals that belong to it?

I'm curious to know if such a collection of data exists, so I could visualize it with a graph, and see how humans compare to other spieces of similar size.
1 vote
0 answers
57 views

Are there worms/snake traveling by rolling? (see youtube video) [closed]

Someone obtained this from a nature simulator : https://youtu.be/l-qOBi2tAnI Is there any animals travelling like this?
2 votes
0 answers
47 views

How to find a model organism's standard data about proteome size and genome size?

I want to know proteome size(the number of proteins not length) and genome size(length) of model organisms like Caenorhabditis elegans, Saccharomyces cerevisiae etc. I found www.uiprot.org and I made ...
-3 votes
1 answer
87 views

Why do we use mice in labs? [closed]

Why do we use mice in labs for experiments targeting humans ? Are they near humans biologically speaking ?
-1 votes
1 answer
36 views

Animal body size determination for abundance

Does an animal being small or large determine its abundance?
0 votes
1 answer
27 views

When comparing oral infection v IV infection in mice, why would the CFU given be different volumes?

In the paper, orally infected mice are given 1x10^9 CFU of C. Rodentium and IV infected mice are given 5x10^7 CFU of the pathogen. Does anyone know if there is a generic reason for this? Thanks in ...
5 votes
1 answer
130 views

Which turtle species was on board the Iranian Space Agency launch in 2010?

They are seen briefly in this video: https://www.youtube.com/watch?v=nZoNdf6hlII The launch made international news, but there was no mention of the species. Here's the entirety of Wikipedia's ...
1 vote
0 answers
22 views

natural characteristics of insects used as human disease model

In this paper [1], the author found that the autism-related genes are conserved between honey bee and human. Thus, this paper providing a means to further explore sociobiology theory. In my opinion, ...
3 votes
2 answers
72 views

Interesting examples of models [closed]

I am studying the general use of models in biology in terms of methodology, applications, usefulness etc, and I would really appreciate any recommendations of some specific examples of models from any ...
0 votes
1 answer
92 views

How to watch a Zebrafish embryo in detail?

How much microscope zoom would I need to watch the development of a Zebrafish embryo in certain detail? Thanks guys!
2 votes
0 answers
38 views

Amount of animals to use for animal trials [closed]

I am working on an independent research project involving animal models. I am unsure how to deterine how many animals (rats) to use for the project. The rats will be injected with different solutions ...
0 votes
1 answer
36 views

Does using animal models for medical research also promote veterinary research on these animal types?

I have been reading about mouse models for studying inflammatory bowel diseases such as Crohn's disease and Ulverative Colitis. For example, according to this publication, a widely used mouse model ...
0 votes
1 answer
33 views

Mice that have been reconstituted with geneX-transduced cells

I read this article in the following: ... Mice that have been reconstituted with geneX-transduced cells Now, someone who is not familiar with animal sciences, what does this exactly mean? ...
3 votes
2 answers
4k views

Can predator-prey relationship be an example of negative feedback?

Predators eat their prey, prey population decreases. This results in the predator population to decrease, so less prey are consumed which causes the prey population to increase. Therefore, if the ...
3 votes
1 answer
292 views

How to give a biological interpretation to this phase portrait?

Consider the following system and analyze its behavior. $$\begin{array}{rl} \frac{dA}{dt} &= A \left( 2-\frac{A}{5000}-\frac{L}{100} \right)\\ \frac{dL}{dt} &= L \left(-\frac{1}{2}+\frac{A}{...
-3 votes
1 answer
59 views

Are there organisms sensing conformations, which we humans can't sense directly? [closed]

Are there organisms which can sense the conformations, which we humans can't sense directly, i.e. without using any equipment? If there are organisms which can sense conformations ("the shape or ...
2 votes
0 answers
256 views

At what g force do bacteria start to pellet down a tube?

I am working with C. elegans and bacteria and I want to get rid of the bacteria they eat by centrifuging the worms without centrifuging the bacteria. I am using a g-force of 600 and the bacteria ...
1 vote
0 answers
29 views

Can C. elegans be raised on Lactobacillus as the only food source?

I'm interested in running some C. elegans experiments for educational purposes, but would like to avoid having to grow or handle E. coli. I was wondering if C. elegans need E. coli specifically, or ...
1 vote
0 answers
70 views

About which cells in the human body do we know most? [closed]

Are there model cells (in the sense of model organisms) in the human body (other than E.coli) about which is known most (with respect to structure, function, metabolism, gene expression, ...) and to ...
1 vote
1 answer
690 views

Why is Mus Musculus a good model organism? [closed]

I'm reading through a number of articles that use partial hepatectomy in Mus Musculus to study the mechanisms for liver regeneration (1, 2, 3). I have no doubt that a better understanding of ...
1 vote
1 answer
36 views

is this true to select 100 volume higher concentration of a drug test?

I am interested in knowing how to find/optimise the concentration needed for a drug effect in cell. and different organism For example, if I use 1 micro molar for treating a cell. Should I use 10 nM ...
2 votes
0 answers
652 views

How much does an experiment on monkeys cost?

Including legal fees, the paperwork, the housing, the food etc. (provided there is already a lab with biomedical lab equipment and space for the housing) for let's say the final testing phase of a ...
3 votes
2 answers
196 views

Do only large birds float?

So, I've noticed a pattern in water fowl (here meaning birds who can take off and land on water, who float in the intervening time) tend to be larger birds. The smallest I know of are gulls. Are ...
0 votes
1 answer
106 views

How many cells does the hermaphrodite version of Caenorhabditis elegans have? [closed]

Wikipedia states: The male C. elegans, for example, has 1031 cells How many cells does the female version have?
1 vote
1 answer
55 views

How good is the reproducibility of preclinical models?

Unofficially, biology researchers always complain how frequently fail to replicate results others have achieved. But of course, such failed experiments are underreported. Is there data, or at least ...
1 vote
0 answers
85 views

0.9% Saline or Ringer's Solution for in vivo work

A few of the labs where I currently work routinely use 0.9% saline for in vivo work (washing out debris during surgery, diluting substances for IP/IV/SC injections, etc.) A few years ago I worked in ...
4 votes
1 answer
207 views

Unknown animal - What could it be?

It's the first time I use this website and I really need help because I'm totally stuck Now I'm in school, but I'm trying to prepare for the Olympics During the preparation, I found the issue on the ...
4 votes
1 answer
2k views

What is the difference between conditional and inducible activation?

In the modern genetically modified animal models, there are not only constitutive mutations which start producing proteins already in the embryo, but also mutations which can be turned on later. I've ...
0 votes
0 answers
109 views

Organ secretions

If an animal secrets an enzyme from an organ that is entirely dedicated for the same secretion, can one or cannot one just use the gene coding for that protein to obtain the protein in vitro. How much ...
1 vote
1 answer
47 views

What motivates birds to make birdsong?

I was pondering the question "Why do humans make music?" and on an intuitive level, my answer was "because of the feelings it evokes of course!" But I then wondered, what about songbirds? Does a ...
3 votes
1 answer
60 views

What is the purpose of narwals' tusks?

I've heard that narwals can grow their tusks up to 16 ft long. What do they need the tusk for? Hunting? Comunication?
3 votes
1 answer
58 views

DNA replacement: new species

This is a hypothetical question What would happen if the DNA of a prokaryote was replaced with the one of a prokaryote of another species, would the cell structures change and adapt to the new DNA ...
2 votes
1 answer
148 views

How do C. elegans manage nutrition?

If there is ample amount of food, do C. elegans worms know when to stop eating or do they store extra energy? Could they put this extra energy to use by moving faster or putting more eggs?
3 votes
1 answer
840 views

What is the difference between a DPY-10, DPY-11, and DPY-13?

My TA mentioned these three mutations of C. elegans since we started working with the worms but seems to skip over what the differences are...
3 votes
1 answer
328 views

Does isolation have any effect upon mouse behavior?

I work with a lot of mice. I don't do any behavioral analysis, I just inject DNA or RNA and do imaging assays. However, I have noticed some effect of isolation on mouse behavior. Normally, the mice ...
4 votes
2 answers
167 views

What is an Ihh-/- mouse?

This one is too basic question: I just came across $Ihh^{-/-}\ $ mouse. Is that means this mouse devoid of that gene Ihh. What is this sign called and are there other such representations?
3 votes
1 answer
75 views

Is there a superterm combining "animal line" and "cell line" in disease models?

Biologists researching diseases will frequently use animal models. The way I understand it, there are species of animals, such as "mouse", and lines of mice, such as ...