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Questions tagged [antibiotic-resistance]

Tag for questions related to the ability of bacteria to adapt to antibiotic agents in there environment through genes present in their genome or acquired from the DNA of other organisms through the process of Transformation.

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Loss of antibiotic resistance due to long term storage

How possible is it for antibiotic resistant bacteria stored for a long time to lose such resistance?
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1answer
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Are there limits to drug resistance?

It's well-known that indiscriminate use of a drug leads to resistance. My question is what the limits on resistance are. It seems obvious that there must be limits: for example I can hardly imagine a ...
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1answer
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How close are we to having phages take over the role of infection control from antibiotics? What developments need to occur?

The discovery of, and research in, the field of phages was overshadowed by the discovery and implementation of antibiotic treatments for infectious disease control. With the rising concern of ...
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1answer
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Why is AMR not widespread?

we know that resistant strains (MDR, XDR, PDR) have arisen in single incidents around the globe but why are these bacteria not common and not spreading quickly as humans keep using antibiotics and ...
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2answers
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Is it true that it is mostly impossible, for any kind of antibiotic, to succeed in killing off every bacteria in a very rich environment?

It is commonly believed that the resistance to antibiotics by micro-organisms is truly evolution at work, and that the recent surge in superbugs may very well be attributed to it. When we refer to a ...
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What effect does taking antibiotics unnecessarily have on future bacterial infections?

I have been told by my biology teacher that you shouldn't take antibiotics unnecessarily because "the body gets used to them" and it reduces the effectiveness of antibiotics against future bacterial ...
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1answer
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Is a wild-type strain more “fit” than its mutant strains?

Question's context In the context of a presentation on mathematical models for antibiotic-resistance bacteria research, someone mentioned that wild type strain (WT) are expected to be more fit than ...
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1answer
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Test of antibiotic A for sensitivity as surrogate of antibiotic B

I am reading the WHO Global Antimicrobial Resistance Surveillance System (GLASS) - Manual for Early Implementation. it mentioned some of the drug-bug combination that will be put under surveillance in ...
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2answers
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Why antimicrobial resistance is based mainly on antibiotic use? [closed]

Why antimicrobial resistance is based mainly on antibiotics use and not so much on antifungal or antivirus drugs? Why, when someone speaks about antimicrobial resistance, refers mostly to antibiotitic ...
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Is it inevitable that antibiotics will become useless in the future due to bacteria immunities?

Antibiotics are developed in an ever smaller amount due to the difficulties of discovering new ones. Bacteria, on the other hand, keep "finding" more ways to render antibiotics ineffective, and they ...
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3answers
286 views

Could plasmids and conjugation mechanisms be used against antibiotic-resistant bacteria? [closed]

I'm surprised no one has mentioned something like this. Plasmids are often exchanged between bacteria, sometimes through conjugation. In particular, conjugation could be considered an "open-port" ...
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0answers
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How quickly do bacteria lose genes after selection has been removed? [duplicate]

If bacteria are subject to a biocide and then that biocide is removed from the population, how quickly will they lose that gene that encodes for resistance?
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1answer
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Why would eating the meat of cows fed with antibiotics trigger an immune response to the antibiotics? [closed]

The document "Antibiotics and Antibiotic resistance" contains the following paragraph: The indiscriminate use of antibiotics in feed stuffs means that humans may receive unwanted doses of ...
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1answer
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Have bacteria evolved antibiotic resistance in a laboratory setting?

Is it possible to breed a strain of bacteria in a laboratory setting so that it gains resistance to an antibiotic, replicating the kinds of resistance seen in wild, and has that been done?
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2answers
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What placement of plasmid parts makes the most sense?

If you want to express the largest amount of a certain or a few proteins using a plasmid, does it make sense for the antibiotic resistance gene to come after genes for proteins you intend to ...
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0answers
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Will dead cells in culture media have any significant impact on Live cells during incubation?

I am generating stable cell lines and have something like 25+ culture flasks to take care of. Ideally I can let dead cells sit in the media with the live adherent without rushing to change media ...
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2answers
383 views

Resistance to Antiseptics

I know that bacteria can become resistant to antibiotics. Why do antiseptics like alcohols, PVP-I, still work on the strains of bacteria we have today? Shouldn't some bacteria have evolved to be ...
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1answer
535 views

Drug and antibiotic resistance in organism [closed]

Out of gram positive or gram negative or both which one is having a higher resistance to drug or antibiotics? How the organism gains that gene for drug or antibiotics resistance.? Kindly explain it in ...
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1answer
355 views

What does completing the course of antibiotics accomplish?

This article from the WHO states: If you stop treatment early, there is a risk the antibiotics won’t have killed all the bacteria that made you sick and that it will mutate and become resistant. ...
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0answers
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After a bacterial infection is dealt with, do any of that colony of bacteria remain?

Suppose that I get a bacterial infection, which my immune system deals with. Are there any remnant bacteria, or are they all gone? Now consider the same scenario, but having been treated with a full ...
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3answers
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Why do we take antibiotics if our immune system already produces them? [closed]

Why do we take antibiotics if our immune system already produces them? Is it because our body doesnt make enough or the specific complementary antibody to fit with the antigen?
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1answer
151 views

Why can bacteria resist topical antibiotics, but not compounds?

The excerpt below is from p 2 of 4, but p 4 of 4 exhibits the review of the entire article by Debra Jaliman, MD on April 17, 2014. Usually, topical antibiotics aren't recommended alone as an acne ...
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1answer
548 views

Does long term use of antibiotics in humans actually lead to a greater risk of infection?

I've read about the overuse of antibiotics leading to antibiotic resistant strains of bacteria, so generally does long term use of antibiotics breed these strains in the bodies of antibiotic users and ...
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1answer
522 views

Which immunosuppression caused by long-term usage of these antibiotics in untreated celiac disease?

These antibiotics include amoxicillin + acidum clavulanicum (beta-lactam, inhibit cell wall synthesis, broad specturm, 3rd gen aminopenicillin) / last part preventing the resistance ceftriaxone (3rd ...